Chime is kept in the stomach until it achieves the proper consistency to flow into the small intestine by the pylorus, a walnut-sized muscle valve at the stomach's output.
The pyloric sphincter is the organ that regulates the passage of food from the stomach to the small intestine. It is a smooth muscle called the pyloric sphincter. Its function during digestion is to regulate the chime flow between the stomach and the small intestine. Chime, which is made up of partially digested food, water, hydrochloric acid, and other digestive enzymes, is produced as a result of the mechanical and chemical breakdown of a bolus. Chime moves gradually through the pyloric sphincter and into the duodenum, where nutritional extraction starts. The time it takes for the stomach to convert food into chime will vary depending on the size and composition of the meal. [Reference needed] Chime that leaves the stomach has a pH of about 2, which is extremely acidic. Cholecystokinin (CCK), a hormone secreted by the duodenum, causes the gall bladder to constrict and release alkaline bile into the duodenum. The pancreas releases digestive enzymes as a result of CCK. A brief segment of the small intestine called the duodenum is situated between the remainder of the small intestine and the stomach.
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