Respuesta :
When substrate binds to the enzyme the structural changes occur bring specific parts of a substrate into alignment with specific parts of the enzyme’s active site.
After binding to the enzyme amino acid side chains in the binding site can then act as acid or base catalysts. It provide binding sites for the transfer of functional groups from one substrate to another in the rearrangement of a substrate. The participating amino acids which are usually widely separated in the primary sequence of the protein are brought close together in the active site as a result of the folding and bending of the polypeptide chain when the protein acquires its tertiary and quaternary structure. Binding to enzymes brings reactants close to each other and aligns them properly which has the same effect as increasing the concentration of the reacting compounds. This explains the process of binding to the enzyme.
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