the interaction between which types of adhesion molecules are required to stop a leukocyte prior to extravastion?

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30-11-2022
Biology

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the interaction between which types of adhesion molecules are required to stop a leukocyte prior to extravastion?

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kumarravichandra kumarravichandra · Answer 1 · 2022-12-04T05:48:36+01:00

The interaction between which types of adhesion molecules are required to stop a leukocyte prior to extravastion is known as intigrins.

A family of plasma membrane proteins is known as integrins. These proteins help the extravastionr matrix and the interior of the cell communicate with one another. The alpha and beta subunits of integrins, which are heterodimeric proteins with two distinct subunits each, are tethered to the plasma membrane by a transmembrane helix.Integrins function as both receptors and signal transducers, and as such, they have binding sites for a variety of extracellular macromolecules. The leucocyte adhesion molecule's beta subunit, also known as CD18, is encoded by the integrin gene. Leukocyte adhesion deficit in humans is caused by mutations in this integrin gene.

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