1. Antigen presenting cell (APC)
2. inflammatory (Cytotoxic)
3. TC (CD8)
4. CD4+ () cell
5. II (TH1)
6. T-cytotoxic (TC, cytotoxic T cells)
7. perforins
8. granzymes
9. I (TH1) cell
10. immune
The development of both cellular and humoral immunity depends on T cell antigen activation, a critical stage in the adaptive immune response. In addition to helping B cells and producing cytotoxic T cell responses, activation is necessary for efficient CD4 T cell responses. In the two signal paradigm, T cells might be activated by concurrently receiving signals from cytotoxic T cells costimulatory molecules and T-cell antigen recognition, or signal-1 and signal-2.
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