the results of the subject's blood tests showed elevated levels of lactate, pyruvate, and lactate dehydrogenase. describe the most likely explanation of these test results by completing the passage. decreased activity of one or more subunits of directly causes to accumulate. the accumulation of this metabolite leads to increased production of which then converts

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30-11-2022
Biology

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the results of the subject's blood tests showed elevated levels of lactate, pyruvate, and lactate dehydrogenase. describe the most likely explanation of these test results by completing the passage. decreased activity of one or more subunits of directly causes to accumulate. the accumulation of this metabolite leads to increased production of which then converts

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Tutorconsortium361 Tutorconsortium361 · Answer 1 · 2022-12-02T11:56:34+01:00

Decreased activity of one or more subunits of PDH complex (the alpha-ketoglutarate dehydrogenase complex, the PDH complex, lactate dehydrogenase) directly causes Pyruvate (pyruvate, lactate, CO2) to accumulate. The accumulation of this metabolite leads to increased production of lactate dehydrogenase_ (the alpha-ketoglutarate dehydrogenase complex, the PDH complex, lactate dehydrogenase) which then converts pyruvate to lactate (pyruvate to lactate, lactate to pyruvate, pyruvate to acetyl CoA, alpha-ketoglutarate to succinyl CoA).

What is pyruvate?

The simplest alpha-keto acid is pyruvic acid, which has a carboxylic acid and a ketone functional group. The conjugate base pyruvate, CH3COCOO, is a metabolic intermediary found in many different cell-wide metabolic pathways.

To learn more about pyruvate from the given link

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