Given the following parameters
Mass of P2O5 = 48 grams
Convert mass to moles
[tex]\begin{gathered} moles\text{ of P}_2O_5=\frac{mass}{molar\text{ mass}} \\ moles\text{ of P}_2O_5=\frac{48}{144.94} \\ moles\text{ of P}_2O_5=0.3312moles \end{gathered}[/tex]Convert moles to molecules uusing the Avogadros constant. According to the Avogadro's constant;
[tex]\begin{gathered} 1mole=6.02\times10^{23}molecules \\ 0.3312moles\text{ of P}_2O_5=0.3312\times6.02\times10^{23} \\ 0.3312moles\text{ of P}_2O_5=1.99\times10^{23}molecules \end{gathered}[/tex]Hence the number of molecules in 48 grams of P2O5 is 1.99 * 10^23 molecules