The majority of the energy is kept as NADH. The citric acid cycle also occurs in the matrix of mitochondria, where pyruvate is converted to acetyl CoA.
With the exception of succinate dehydrogenase, which is encased in the inner membrane of the mitochondrion, almost all of the enzymes involved in the citric acid cycle are soluble. The byproduct of glycolysis, pyruvate, is converted into acetyl CoA in the mitochondria for the following process. the citric acid cycle, wherein the mitochondrial modification of acetyl CoA results in the production of energy precursors. The cytoplasm is the location of glycolysis. The citric acid cycle takes place within the mitochondrion's mitochondrial matrix, and internal folded mitochondrial membranes are where oxidative metabolism takes place (cristae).
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