An inhibitory postsynaptic potential (ipsp) occurs when ligand-gated chloride ion channels open.
What is inhibitory postsynaptic potential (ipsp) ?
A type of synaptic potential known as an inhibitory postsynaptic potential (IPSP) decreases the likelihood of an action potential being produced by a postsynaptic neuron.
- An inhibitory postsynaptic potential (IPSP) is a brief hyperpolarization of the postsynaptic membrane brought on by the entry of negatively charged ions. When a dendritic-connected inhibitory presynaptic cell fires an action potential, an IPSP is received.
- Inhibitory postsynaptic potentials, or IPSPs, can happen at any chemical synapses that interact by releasing neurotransmitters.
- Take a look at a neural synapse that uses the transmitter GABA as an illustration of inhibitory postsynaptic action. The GABA receptors at such synapses normally activate channels that are only permeable to Cl-. Negatively charged chloride ions can cross the membrane when these channels open.
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