To travel from byzantine empire to the Persian empire, a merchant would have to go in the eastward direction since the Byzantine empire is located on the eastern side of Europe.
Byzantine empire was another name for the eastern Roman empire with Constantinople as its capital. After the decline of the western Roman empire, the eastern part survived and came to be identified as Byzantine during the Late Antiquity and the Middle Ages.
The Persian Empire was located on the westward direction of the Byzantine Empire. It lasted for approximately 200 years after which it was conquered by Alexander the Great.
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