The equilibrium constant for the un-catalyzed reaction is 0.9
The enzyme triose phosphate isomerase catalyzes the reaction in the forward direction as part of the glycolytic pathway. It follows simple Michaelis-Menten kinetics.
Typical cellular concentrations:
triose phosphate isomerase = 0.1 nM
dihydroxyacetone phosphate = 5 µM
glyceraldehyde-3-phosphate = 2 µM
So, equillibrium constant is
K = [tex]\frac{[P]}{[S]}[/tex]
K = [tex]\frac{ glyceraldehyde-3-phosphate}{dihydroxyacetone phosphate}[/tex]
Therefore, The equilibrium constant for the un-catalyzed reaction is 0.9
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