Why don't prokaryotic cells divide through mitosis? Mitosis requires a cell membrane, and prokaryotes don't have a cell membrane. Mitosis and cytokinesis require cytoplasm, and prokaryotes don't have cytoplasm. Mitosis is division of the nucleus, and prokaryotes don't have a nucleus. Mitosis requires DNA and chromosomes, and prokaryotes don't have chromosomes.

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Answer:

Prokaryotic cells, on the other hand, do not undergo mitosis and therefore have no need for a mitotic spindle.

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