Identify one example from the scientific literature of how a chemogenetic or optogenetic modulator was used to correct signaling in a disrupted cellular pathway.

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27-07-2020
Biology

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Identify one example from the scientific literature of how a chemogenetic or optogenetic modulator was used to correct signaling in a disrupted cellular pathway.

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hihirasohail hihirasohail · Answer 1 · 2020-07-31T04:08:43+02:00

Answer:

A chemogenetic based technique known as Designer Receptors Exclusively Activated by Designer Drugs (DREADD) has been used to study the pathway of neurons in the dorsomedial striatum in mice addicted to alcohol.

Explanation:

Transgenic mice were used in this research and synaptic transmissions were monitored. It was found that DREADDs could indeed have an impact on these transmissions by way of either silencing or activating them.