Answer:
When TPMT DNA sequence is known, it is possible to determine the risk of developing serious side effects in case of being treated with immunosuppressive drugs derived from thiopurine such as azathioprine, mercaptopurine and thioguanine.A person with little or no activity of TPMT presents risk of developing serious side effects so the medication needed to cure your disease would be changed. On the other hand, a low or intermediate TPMT activity is a sign of risk of developing drug toxicity.