A 67-year-old patient who has a history of pleural and pericardial effusions is given sargramostim for the first time. What precaution should the nurse take when administering the first dose of the drug?
-Check for effects such as respiratory distress, hypotension, and syncope in the first 20 minutes.
-Administer diphenhydramine along with sargramostim to increase therapeutic effect.
-Rub ice gently at the injection site before and after injection.
-Rotate injection sites among the upper arms, abdomen, and thighs.