A 42-year-old man presents with severe abdominal pain in the mid-epigastric region. The pain began 3 days ago with an intensity of 10/10, concomitant nausea, and vomiting (on 2 occasions). The patient denies any significant past medical history. BP is 86/58, and pulse is 112; temp is 101.5° F. There is rebound tenderness in the midepigastric area; bowel sounds are absent, and there is a positive Cullen's sign. The rest of the physical exam is within normal limits. What are the 2 most common causes of acute pancreatitis?

A) Hyperlipidemia and hypercholesterolemia
B) Pancreatic cancer and chemotherapeutic drugs
C) Gallstones and alcohol abuse
D) Abdominal trauma and postoperative period
E) Peptic ulcer disease and cystic fibrosis